objective:  anchomanes difformis is a member of the plant family araceae which is used as a diuretic but also has other medicinal applications. this study investigates the dietary effects of a. difformis on the kidneys of adult wistar rats. materials and methods: sixteen rats were used and were weighed, before and after the experiment. all rats were randomly divided into four groups. all groups...

The FKBP-12-rapamycin associated protein (FRAP, also known as mTOR and RAFT-1) is a member of the phosphoinositide kinase related kinase family. FRAP has serine/threonine kinase activity and mediates the cellular response to mitogens through signaling to p70s6 kinase (p70(s6k)) and 4E-BP1, resulting in an increase in translation of subsets of cellular mRNAs. Translational up-regulation is block...

Differences in susceptibility to oxidative stress between males and females have been postulated. Several methods have been developed to assess the total antioxidant capacity of human serum or plasma, but just recently some of them were employed for measurement of antioxidant capacity of tissues. In this study, we measured and compared antioxidant capacity of heart, kidney, liver and brain tiss...

Harmine is a harmal-derived alkaloid with antioxidant properties. The morphine produces free radicals and plays a key role in the pathogenesis of kidney disease. This study was designed to evaluate the effects of harmine against morphine- induced damage to the kidneys of rats. In this study, 64 male rats were randomly assigned to 8 groups: saline and morphine treated groups; harmine groups (5, ...

The present study was aimed at evaluating magnesium content, ferric reducing antioxidant power (FRAP) and lipid peroxidation in selected tissues of rainbow trout during their development. For mineral and biochemical assay, samples of liver, kidney, gills and blood were taken from fish. Magnesium concentration ranged between 35.5 and 249.2 mg·kg⁻¹ wt/wt. Most magnesium was found in the gills and...

considering that the involvement of oxidative stress has been implicated in the toxicity of organophosphate insecticides, the objective of the present study was to investigate antioxidants and oxidative stress markers in the liver and kidney of wistar rats treated with chronic doses of diazinon. in addition, the effect of tert-butylhydroquinone (tbhq), a food-additive antioxidant, on attenuatio...

antioxidant activity of aerial part of cytisus scoparius, link (family leguminosae) was studied both by in vitro and in vivo models. different concentrations of different extracts of chloroform, ethyl acetate, methanol and hydroalcoholic extracts of plant were investigated for in vitro antioxidant activity using the thiocyanate method. the hydroalcoholic extract exhibited highest inhibitory act...